Radja Nainggolan will be out for "a while" after the midfielder was injured in Inter's derby victory against AC Milan, said Luciano Spalletti.
Nainggolan limped off after half an hour of Sunday's Serie A clash at San Siro, where Inter won 1-0 thanks to a late Mauro Icardi header.
The former Roma star appeared to sustain the injury in a heavy tackle from Lucas Biglia that saw the Milan midfielder booked, although Nainggolan also caught the Argentina international in the incident.
Nainggolan initially played on but after he was on the end of another firm challenge he was replaced by Borja Valero.
And Spalletti suggested Nainggolan could face a lengthy lay-off, with Inter next in action against Barcelona in the Champions League on Wednesday.
"Nainggolan has been chopped down," Spalletti said to Sky Sport Italia.
"We have to take him to the hospital and see. He won't be with us for a while."
|￣￣￣￣￣￣￣￣￣￣￣|— Inter (@Inter_en) October 21, 2018
\ (•◡•) /
| | pic.twitter.com/HQv85J7IYw
Both teams had a goal ruled out for offside while Stefan de Vrij hit the post in the first half, but Spalletti was in no doubt the result was fair.
"It's obvious Inter deserved it, we played from start to finish in their half, pressed high and went for it," the coach added.
"Therefore, we deserve compliments. Not because we wanted it more, but because we played better. If you say to me, 'The team that wanted it more got the win', that is not accurate. The team that played better football won the game.
"I came here to win, not to just sit on a bench for a season and bring home a salary. I came here to organise the future of Inter and the players must do the same.
"I liked that after the final whistle, Icardi said we must find consistency and keep pushing. Inter chose us to bring this side back to the level that the fans deserve. It is our job, we must do it with a sense of belonging and prove they were right to choose us.
"It's dangerous when you press high, as there is always the risk of conceding a counter, but we were perfect and forced Milan to continually lose the ball. We ensured Milan were incapable of playing their quality passing game that Gennaro Gattuso had spoken about."
|Rams-Chiefs rollercoaster was the NFL´s modern-day masterpiece|
|Ronaldo an AC Milan target in 2017, confirms Fassone|
|Farah could get back on track at Tokyo Olympics|
|PSG still waiting on Alves and Kurzawa|
|Atalanta reject Gasperini to AC Milan speculation|
|Edmonton Oilers name Hitchcock new head coach|
|JR Smith on Cleveland Cavaliers: Tanking ´was always the plan´|
|Chester signs new Wakefield deal|
|F1 Raceweek: Countdown on to Alonso farewell|
|Rain disrupts Lorenzo´s Honda debut|
|VAR a possibility for Champions League knockout rounds|
|FFP vulnerable in areas, says UEFA president Ceferin|
|Sri Lanka draft in uncapped Peiris to replace Dananjaya|
|Coman back in Bayern training but Lewandowski has knee injury|
|Qalandars land De Villiers in PSL draft, Smith second pick|
|F1 changes helped less talented drivers on the grid - Alonso|
|Agnelli: No super league talks since 2015|
|I hope from now on it only gets better - Floersch update on horror crash|
|Calf injury rules Ashton out of Australia match|
|Halfpenny to miss South Africa clash|
|Hard for Lazio to hold on to Milinkovic-Savic, says Lotito|
|Australia´s next generation pay tribute to retiring Cahill|
|Bairstow pushing hard for Test recall|
|Cane eyes 2019 Super Rugby return after neck break|
|Van Dijk finds time to console referee during Dutch delight|
|Cahill sheds tear at end of phenomenal Australia career|
|WATCH: Pelicans coach Gentry interviews himself|
|Where does Chiefs-Rams classic rank among NFL´s highest-scoring matches?|
|Australia 3 Lebanon 0: Boyle bags brace on Cahill farewell|
|Guendouzi underlines desire to represent France|
|I might need a couple of drinks to relax after that! - Rams coach McVay|
|Juventus´ Alex Sandro has Premier League ambition|
|Ederson taking goalkeeping to another level, says City hero Weaver|
|Ceferin dismisses "super league" plans as fiction|
|Rams defeat Chiefs in one of the highest scoring games in NFL history|
|Kemba Walker leads Hornets to win over Celtics|
|Gomez praises ´top player´ Van Dijk, Stones|
|Cricket Australia to maintain Smith, Warner ball tampering bans|
|Brazil´s Tite encouraged by Neymar captaincy|
|Holmes set for NFL switch after Cronulla release|
|Dier encourages English youngsters to follow Sancho´s lead|
|Southgate promises further changes to England squad|
|Jones sceptical over Pocock injury|
|Sane encouraged despite Germany´s ´annoying´ Nations League draw|
|Character got Netherlands through, says Koeman|
|Netherlands´ focus still on Euros - Van Dijk|
|Ireland will be ready for qualifiers, insists O´Neill|
|Smith undergoes successful surgery, Redskins sign Sanchez|
|Germany 2 Netherlands 2: Dramatic five-minute fightback seals Oranje progression|
|Denmark 0 Republic of Ireland 0: Thrills at a premium again in Aarhus|
|O´Brien could return for start of Six Nations|
|Cavani: Neymar and I are ´friends, brothers, team-mates´|
|Pothas named Windies interim head coach|
|LA Galaxy planning for Ibrahimovic stay|
|NFL will return to Mexico City in 2019|
|Broner vows to end Pacquiao´s career in Las Vegas|
|UEFA should punish PSG and Man City, says LaLiga chief|
|Teenage driver Floersch has ´no fear of paralysis´ after operation|
|Mancini bemoans Italy´s misfortune in front of goal|
|Sprint legend Johnson ´pretty much back to normal´ after stroke|
|Bournemouth defender Adam Smith out for three months|
|World champions France out to end 2018 on a high|
|I told him there´s no future in football! A-Rod relieved to be ignored by Mahomes|
|Dembele must focus and be more responsible - Suarez|
|Neymar could return one day – Barca chief|
|Cole backs West Ham to keep Arnautovic|
|Injury rules Bernardo Silva out of Poland clash|
|Lamar Jackson debut start ´spectacular´ - Ravens coach Harbaugh|
|Babar run out the turning point, laments Sarfraz|
|West Ham boost London Stadium capacity to 60,000|