The quarter-final line-up for the Champions League will be completed this week, with Tuesday's ties both finely balanced.
Manchester United had David de Gea to thank for a battling 0-0 draw in Sevilla, but will be hoping to spend more time on the front foot at Old Trafford.
Roma have the benefit of an away goal from the first leg against Shakhtar Donetsk, but will need to score at least once to progress after losing 2-1.
Here we look at some of the best Opta numbers ahead of the two matches.
Roma v Shakhtar Donetsk
4 - Shakhtar Donetsk have won four of their five competitive games against Roma (L1), all in the Champions League.
52 - More than half of the teams who lose the first leg of a Champions League knockout game away from home 2-1 end up progressing (52 per cent - 12/23).
4 - However, Roma have been eliminated from all four Champions League knockout ties in which they have lost the first leg (home or away).
1 - The Ukrainian side are aiming to reach the Champions League quarter-finals for the first time since the 2010-11 campaign – which they did so by beating Roma 6-2 on aggregate in the round of 16.
3 -The Italian side have kept a clean sheet in each of their last three Champions League home games, winning the last two (D1).
Manchester United v Sevilla
1 - Manchester United have only lost one of their last nine home Champions League games against Spanish sides (W5 D3), that came against Real Madrid at this stage in 2012-13.
70 - Of the away sides who have drawn the first leg of a Champions League knockout tie 0-0, 70 per cent end up progressing to the next round (21/30).
15 - Manchester United haven't managed to score more than one goal in any of their last 15 Champions League encounters with Spanish opposition (seven goals in total).
0 - Sevilla have never won a Champions League game in England (D1 L3), with that one draw coming at Liverpool in this season's group stages.
1 - Starting with the 2011 final, Manchester United have only won one of their last eight Champions League knockout games (D3 L4).
7 - Jose Mourinho has only lost seven of his previous 69 Champions League home games as manager (W48 D14), though five of those defeats have been against Spanish opposition.
|Broad strikes again – the Opta data behind the England bowler´s 400th wicket|
|Wenger told Wilshere he could leave Arsenal|
|An India hat-trick and THAT Ashes annihilation: Broad´s finest Test spells|
|Broad removes Latham to claim 400th Test wicket|
|If you play for Atletico, you must be committed – Koke responds to Griezmann speculation|
|LeBron´s historic night leads Cavs past Raptors, Howard tallies rare 30-30|
|Del Potro, Cilic loom for Haase and Herbert|
|Giggs: Bale will feature for Wales in China Cup|
|Serena releases statement after skipping media following Miami loss|
|England bowled out for 58 in 130-year Test low|
|Maradona: Messi doesn´t have to prove himself by winning World Cup|
|Cavs tally worst defensive half of season against Raptors|
|McIlroy, Johnson stunned on day one in Austin|
|Cristiano Ronaldo hasn´t asked to leave Real Madrid amid China links – Perez|
|Oakland Athletics allowing fans to pick price of tickets, all proceeds to charity|
|Ginobili: Spurs not expecting Kawhi Leonard to return this season|
|Trout, Angels brass confident Shohei Ohtani will be a star|
|Osaka wanted to impress Serena with stunning Miami Open win|
|Manchester United apply for professional women´s team|
|Bolt hopes fellow Jamaican breaks his world record|
|Bolt a fan of Ronaldo, but compares his talent to Messi´s|
|Outstanding Osaka knocks out Williams in Miami opener|
|Del Potro ´tired´ heading into Miami Open|
|Heynckes definitely leaving at end of season, claims Ze Roberto|
|Joshua tells Wilder to be ´realistic´ in negotiations|
|Shaw issue a distraction from Manchester United´s failures, says Neville|
|Hamsik withdraws from Slovakia squad|
|RFU backs Jones despite awful Six Nations|
|Hamilton eyes Melbourne pole record, 100 club for Vettel? - Australian GP in numbers|
|Griezmann backs Pogba to prove doubters wrong for France|
|Sanchez ´expected something better´ from Manchester United move|
|WATCH: Thomas conjures up great escape in Austin|
|Javi Martinez in the dark over Spain squad omission|
|Jones should have managed England workload - Flood|
|Giggs feeling the tension ahead of Wales debut|
|Juventus confirm Alex Sandro thigh injury|
|Hart praises ´loyal guy´ Southgate amid World Cup axe fears|
|Windies singing in the rain as they clinch World Cup spot|
|I miss Morata, says recalled Costa|
|I can improve even more at Manchester City - Bernardo Silva|
|Neymar will be fit for the World Cup, insists Ronaldo|
|Costa thinks Griezmann will stay at Atletico Madrid|
|Third DRS zone added for Australian Grand Prix|
|Ferdinand worried by England´s World Cup striker options|
|Hamilton an F1 great - Fittipaldi|
|Stam leaves Reading after wretched run|
|Neymar is great, we´ll see if he joins Real Madrid – Asensio|
|Appalling racism must stop - Inglis|
|Maguire tips ´nightmare´ Vardy to replace injured Kane|
|Red Bull duo: Mercedes still the team to beat|
|Wait and see - Root refuses to confirm new-ball role for Broad|
|Malcom ready to leave Bordeaux and chase Bayern ´dream´|
|Surprised Smith says Rabada appeal verdict draws ´line in the sand´|
|Asensio insists Zidane was not unfair to him|
|Griezmann wants future resolved before World Cup|
|F1 2018: Hamilton v Vettel - the race for five titles|
|Nocerino wants Conte return after Italy´s World Cup ´disaster´|
|Celtics capitalise on Thunder meltdown, Harden scores 42 points|
|Jason Day hungry to reclaim top ranking: My game is close|
|Iconic 2002 World Cup haircut was media distraction, reveals Ronaldo|
|New Zealand star Taylor fit for day-night Test|
|Teenager Anisimova to face Muguruza in Miami|
|McIlroy credits Wayne Rooney for improved putting|
|Stokes return a ´huge boost´ for England – Root|
|Wright: Difficult for Liverpool sensation Salah to resist Real Madrid|
|Yaya Toure yet to report for international duty, confirm Ivory Coast|
|Masters favouritism could hinder Woods, Thomas claims|
|I wish I could still play with him – Ortiz on Red Sox addition Martinez|
|Morrison confirms plans to play for Jamaica|
|Warriors target Friday return for Curry against Hawks|