The quarter-final line-up for the Champions League will be completed this week, with Tuesday's ties both finely balanced.
Manchester United had David de Gea to thank for a battling 0-0 draw in Sevilla, but will be hoping to spend more time on the front foot at Old Trafford.
Roma have the benefit of an away goal from the first leg against Shakhtar Donetsk, but will need to score at least once to progress after losing 2-1.
Here we look at some of the best Opta numbers ahead of the two matches.
Roma v Shakhtar Donetsk
4 - Shakhtar Donetsk have won four of their five competitive games against Roma (L1), all in the Champions League.
52 - More than half of the teams who lose the first leg of a Champions League knockout game away from home 2-1 end up progressing (52 per cent - 12/23).
4 - However, Roma have been eliminated from all four Champions League knockout ties in which they have lost the first leg (home or away).
1 - The Ukrainian side are aiming to reach the Champions League quarter-finals for the first time since the 2010-11 campaign – which they did so by beating Roma 6-2 on aggregate in the round of 16.
3 -The Italian side have kept a clean sheet in each of their last three Champions League home games, winning the last two (D1).
Manchester United v Sevilla
1 - Manchester United have only lost one of their last nine home Champions League games against Spanish sides (W5 D3), that came against Real Madrid at this stage in 2012-13.
70 - Of the away sides who have drawn the first leg of a Champions League knockout tie 0-0, 70 per cent end up progressing to the next round (21/30).
15 - Manchester United haven't managed to score more than one goal in any of their last 15 Champions League encounters with Spanish opposition (seven goals in total).
0 - Sevilla have never won a Champions League game in England (D1 L3), with that one draw coming at Liverpool in this season's group stages.
1 - Starting with the 2011 final, Manchester United have only won one of their last eight Champions League knockout games (D3 L4).
7 - Jose Mourinho has only lost seven of his previous 69 Champions League home games as manager (W48 D14), though five of those defeats have been against Spanish opposition.
|Ryder Cup 2018: Team Europe profile|
|Patriots´ Gronkowski threatened to retire if traded to Lions|
|Ryder Cup 2018: Four reasons why Europe will win|
|Tigres and Monterrey condemn violence that leaves fan in intensive care|
|Williams baffled by coach´s claim he sent her US Open final signals|
|Ryder Cup 2018: A sporting spectacular you cannot afford to miss|
|Cricket Australia closes investigation into Moeen claim|
|Zlatan impressed by ´MVP´ singer|
|Modric hoping to complete FIFA and UEFA double at Best Awards|
|Mickelson never doubted Woods would win again|
|Woods looked like Tiger of old in 80th PGA Tour win|
|Chelsea were too slow against West Ham - David Luiz|
|Tottenham star Kane acknowledges sub-par start|
|Rashid signs one-year all-format deal with Yorkshire|
|Brady and Patriots crash to back-to-back defeats|
|Gundogan looking forward to ´real test´ against Liverpool|
|Cubs move closer to clinching NL Central|
|Valverde bewildered by Lenglet red card as Barca boss questions VAR|
|Cronk a ´long shot´ to play in NRL Grand Final|
|Cleary re-signs with Panthers until 2024|
|Bills stun Vikings, Chiefs QB Mahomes impresses again|
|Tiger feels he can surpass Snead´s record after 80th victory|
|Ronaldo mentally stronger than others, says Allegri|
|MLS Review: Ibrahimovic scores as Galaxy end seven-game skid, Dallas reclaim top spot in west|
|Rose told Woods it was ´about time´ after win|
|Dustin Johnson regains number one ranking|
|Pogba: Sanchez will deliver at Man United|
|Federer, Zverev help Europe defend Laver Cup|
|I couldn´t sit or stand – Tiger Woods reflects on back woes after ending drought|
|Snead´s record in sight – Tiger Woods´ 80 PGA Tour wins|
|Nicklaus, Magic Johnson, McIlroy and Kane – Sports stars celebrate Tiger´s Tour win|
|Tiger Woods season in review: Tour Championship win caps remarkable comeback|
|49ers fear QB Garoppolo suffered torn ACL|
|World of golf is proud of Woods – Rose|
|WATCH: Tiger followed by incredible sea of fans at East Lake|
|Three takeaways from the 2017-18 PGA Tour season|
|Mbappe shows off signed Pele shirt|
|Tiger timeline: Woods´ fall and rise|
|Spieth´s breakthrough, Garcia´s Masters moment - Events between Tiger´s triumphs|
|Tiger Woods: I was close to tears on the last hole|
|Woods earns first win since 2013; Rose claims FedEx Cup|
|Pogba implores Manchester United to ´attack, attack, attack´|
|Valverde, Busquets and Vidal criticise Lenglet dismissal|
|Tiger Woods: The stunning statistics|
|Fitness hindering Dybala form, says Allegri|
|BREAKING NEWS: Woods claims first title since 2013, Rose wins FedEx Cup|
|Povetkin struggles leave Joshua with no Wilder fear|
|Guardiola targets Barca, Bayern dominance with Premier League priority|
|Centurions Rohit and Dhawan put India in final|
|Eagles top Colts as Wentz makes his return|
|Barcelona 2 Girona 2: Stuani brace punishes Lenglet red|
|Frosinone 0 Juventus 2: Ronaldo redeemed as champions extend perfect start|
|Gattuso: No alibis for two-faced AC Milan|
|Bangladesh hold on despite late Afghanistan charge|
|Composed Woods hits turn with five-shot lead|
|Chiefs´ Mahomes has another record-breaking Sunday|
|Saints QB Drew Brees passes Brett Favre for most career completions|
|Emery hints Leno may need patience after Cech display|
|Picamoles scores four as Montpellier batter 14-man Toulouse|
|Messi breaks LaLiga record|
|Worcester fend off prowling Tigers, Sarries go top|
|AC Milan 2 Atalanta 2: Last-gasp Rigoni rescues a point|
|Neymar keen to repay supporter affection|
|Pellegrini rues West Ham´s wastefulness|
|Paris Saint-Germain´s positive response buoys Tuchel|
|Lewis rekindles fond memories with Vilamoura triumph|
|Arsenal 2 Everton 0: Lacazette, Aubameyang extend winning streak|
|Stephens suffers as Osaka withdraws in Wuhan|
|Rhinos run riot to secure Super League status|
|Risk brings reward for victorious Marquez|