Virat Kohli's century helped all but clinch the third Test for India on day three as England were set the task of a record-high chase at Trent Bridge.
The India captain began the day at the crease and contributed to a 113-run, 289-ball stand for the third wicket with Cheteshwar Pujara (72) en route to a knock of 103 and a 521-run lead after a declaration.
With nine overs and two days remaining, England required a fourth-innings total far beyond the West Indies' record successful chase of 418 in a 2003 Test against Australia.
And India's grasp on the third match - a belated foothold in a series they trail 2-0 - was scarcely loosened by the embattled hosts' feat of reaching the close on 23 without loss, still 498 runs short of victory.
Another miserable day beckoned for England when Pujara was dropped on 40 by Jos Buttler at slip, failing in a one-handed catch low to his left.
Pujara and Kohli kicked on, while the hosts lost wicketkeeper Jonny Bairstow to injury as he took a blow to his left hand after misjudging a James Anderson delivery. Buttler took the gloves and scans confirmed a small fracture to Bairstow's middle finger.
The two India batsmen reached their respective half-centuries with singles in successive overs and continued beyond lunch, before the partnership was finally ended as Pujara was caught by Alastair Cook off Ben Stokes.
However, vice-captain Ajinkya Rahane, who partnered Kohli for 159 - India's highest stand of the series - in the first innings, arrived in the middle and England made no further progress before tea as the lead stretched beyond 400.
And Kohli's second hundred of the tour arrived with a four shortly after a thick edge flew through Keaton Jennings' hands at gully.
The skipper did not last much longer as he was trapped lbw by Chris Woakes, with Rishabh Pant (1), the next man in, quickly following as Cook caught him off the bowling of Anderson.
That slight wobble did little to slow India down and only after Adil Rashid (3-101) had removed both Rahane (29) and Mohammed Shami (3), with Hardik Pandya unbeaten on 52, did Kohli call the innings to an end at 352-7.
Cook (9 not out) and Jennings (13 no) at least ensured England made it to day four without further damage, but a daunting challenge awaits in Nottingham.
|Button enjoying racing for first time in years|
|Dortmund chief not planning Pulisic sale|
|Theismann: Smith leg break ´heart-wrenching´ to watch|
|Wolves defender Jonny suffers knee injury|
|Holmes to meet with Sharks amid NFL switch talk|
|LeBron made 51 points ´look easy´, says Walton|
|McGuire signs four-year deal with Cowboys|
|Bears beat Vikings to extend NFC North lead|
|Peng overcomes Davis in Houston final|
|Kerr says this has been his toughest stretch as Warriors coach|
|LeBron scores 51 in Lakers´ win, Warriors fall to Spurs|
|Win more than Djokovic? Let´s chill out – Zverev|
|Steelers´ rally highlights wild day of close, last-minute finishes|
|Modric not worried about Ballon d´Or|
|Saints pull away for blowout victory over Eagles, extend winning streak to nine|
|Martinez laments loss of control by Belgium|
|Logano claims first NASCAR Cup championship|
|Luis Enrique delighted with attitude of Spain´s squad|
|Stevens tells Celtics to get ´tougher´|
|Griezmann: Being Messi´s lieutenant played a part in rejecting Barcelona|
|Curry proud of how Warriors handled Green-Durant incident|
|Courtois: Belgium thought Nations League job was done|
|Howell ends 11-year title drought to deny record-breaking Rodgers|
|Robben dismisses Bayern title talk|
|Huge blow for Redskins as QB Smith breaks tibia and fibula|
|Switzerland 5 Belgium 2: Seferovic treble crowns incredible comeback|
|Titans DC Pees taken to hospital during Colts game|
|Spain 1 Bosnia-Herzegovina 0: Debutant Mendez spares Morata´s blushes|
|Peterson goes sixth on rushing touchdowns list|
|Titans QB Mariota suffers elbow injury|
|Djokovic hails much-improved Zverev|
|Arnautovic refuses to discuss West Ham future after Austria win|
|Redskins QB Smith carted off after gruesome ankle injury|
|Jaguars shut down Jalen Ramsey trade rumours|
|Classy Zverev revels in victory, hails defeated Djokovic|
|Forget the Nations League was ever invented, jokes Northern Ireland boss O´Neill|
|Magnificent Zverev claims ATP Finals title|
|Mahrez double fires Algeria to 2019 AFCON|
|Mbappe hoping for French winner of Ballon d´Or|
|Northern Ireland 1 Austria 2: Last-gasp winner denies hosts maiden Nations League point|
|Teenager admits assaulting Wales great Thomas|
|Browns deny Condoleezza Rice is candidate for head coaching job|
|Koeman: Netherlands not favourites for Germany clash|
|Dalic ´not sad´ but blames fatigue for Croatia relegation|
|Proud Southgate hails England hero Kane as world´s best goalscorer|
|Last-gasp Exeter penalty try shatters Bristol|
|Mbappe dismisses talk of Cavani-Neymar rift|
|Keita will do ´great things´ for Liverpool – Mane|
|Mourinho needs time to fix Manchester United - Veron|
|Southgate sees progress as England reward loyal support|
|Miller hungry to ´knock out a Brit´ after Dinu demolition|
|Yasir, Hasan put Pakistan in control with five-wicket hauls|
|England´s resilience delights Kane as Three Lions secure Nations League Finals spot|
|Kane proves Nations League importance to England in Wembley decider|
|Muller, Hummels still important for Germany, says Low|
|Tevez in line for start in Copa Libertadores final second leg|
|England 2 Croatia 1: Kane able to secure Nations League Finals spot|
|It doesn´t sound real - Molinari stunned by 2018 exploits|
|Wales legend Thomas victim of alleged homophobic attack|
|Marquez crashes again as Dovizioso wins rain-interrupted Valencia GP|
|Warriors owner denies taking sides following Green-Durant spat|
|Alisson can become a global great, says Dida|
|The Sunday Seven - 7 Key Opta facts for NFL Week 11|
|Teen driver ´fine´ after sustaining spinal fracture in F3 crash|
|Willett wins first title since Masters triumph, Molinari tops Race to Dubai standings|
|Southgate overcomes ´stigma´ of being sacked to thrive with England|
|Anthony to Lakers ´not a question for myself´, says LeBron James|
|Warriors´ Stephen Curry staying ´cautious´ with injury recovery|
|Gunter hopes Bale can help family jet in to witness Wales record|
|Root pleased to practice what he preached|